Đào Thị Cẩm Minh1,2, Phạm Thị Thanh Hà2,*, Vũ Tùng Lâm2, Nguyễn Thế Anh2, Nguyễn Thị Kiều Anh2
1Đại học Y Dược Huế, Đại học Huế; 2Đại học Dược Hà Nội
*Email: thanhha.pham@hup.edu.vn
A high-performance thin layer chromatographic (HPTLC) method was established for identification and quantification of glimepiride, glipizide, gliclazide, glibenclamide adulterated in herbal products by HPTLC. The matrix was extracted by methanol, the chromatographic separation was performed on thin layer chromatography plates with a mixture of n-butyl acetate contained with 0.5% formic acid as mobile phase. The method was validated according to AOAC 2016 with high specificity and precision; detected 8 positive samples with glibenclamide.
Journal of Medicinal Materials, Vol. 24, No 6/2019 (Page 346 - 351)
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