Evaluation of Blood Glucose Lowering Effects of the Extract from ST Remedy
Đào Thị Thanh Hiền1, Vũ Văn Điền2,*
1Đại học Dược Hà Nội; 2Đại học Đại Nam
*Email: thanhhiendao@gmail.com
The effects of a water extract (2,5 : 1) of ST remedy on plasma glucose were investigated in normoglycemic and diabetic mice. Orally repeated administration of the extract at the dose of 5 g/kg mice and 10 g/kg mice for 3 and 4 weeks significantly induced lower plasma glucose levels compared to controls in normoglycemic mice. The treatment of the extract at the dose of 5 g/kg or 10 g/kg for 10 to 20 consecutive days significantly attenuated fasted blood glucose and hyperglycemic in oral glucose tolerance test in alloxan-induced diabetic mice. In adrenalin -induced diabetic mice, blood glucose was significantly decreased in in treated groups at dose of 10 g/kg as compared to the diabetic control. These results suspected the use of ST extract to manage diabetes mellitus.
Journal of Medicinal Materials, vol. 24, No 6/2019 (Page 368 - 374)
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