DETERMINATION OF CEDROL CONTENT OF CEDARWOOD OILS

14. DETERMINATION OF CEDROL CONTENT OF CEDARWOOD OILS

For the determination of cedrol in cedarwood oils, Rabak174 has suggested the following method :
One hundred parts of oil are agitated vigorously with 6 parts of 65% alcohol (by volume) for one to two minutes in a widemouthed, stoppered flask. Sudden and complete solidifications of the emulsion thus formed usually result if the oil contains a sufficient quantity of cedrol. If it fails to solidify, add a small quantity of crystalline cedrol to the emulsion, and cool in a refrigerator for several hours. Filter the solidified mass with the aid of a well cooled Blichner funnel and wash the fine silky crystals with a few drops of cold 98% alcohol. Weigh the dry crystals. The cedrol may be purified by dissolving it in hot alcohol, then cooling and filtering the mass.
In general, an analytical method based upon the actual separation of a constituent by physical means will not give completely accurate results. However, comparative data may be obtained provided all experimental conditions are carefully controlled.
This method appears to be of value only for obtaining comparative data when two oils are examined simultaneously; all experimental conditions should be maintained as identical as possible.
-----------------------
174 Am. Perfumer 23 (1929), 727.

0 Comment:

Post a Comment

 
© Pharmacognosy | Plants | herbal | herb | traditional medicine | alternative | Botany | © Copyright 2012 ; Email: epharmacognosy@gmail.com