Rescinnamine-Synonyms Reserpinine; Anaprel; Apoterin S; Cartric; Cinnaloid; Moderil

C. Rescinnamine

Synonyms Reserpinine; Anaprel; Apoterin S; Cartric; Cinnaloid; Moderil;

Biological Sources It is obtained from the roots of Rauvolfia serpentina (L.) Benth. (Apocynaceae)

(Rauvolfia, Chandra, Sarpaganda).

Chemical Structure

3, 4 5-Trimethoxy-cinnamic acid ester of methyl reserpate; (C₃₅H₄₂N₂O₉).

Isolation Rescinnamine may be isolated from step (5) onwards as described under Morphine.

Characteristic Features

1. It is obtained as fine needles from benzene having mp 238-239°C (under vacuum).

2. Its specific optical rotation is [α]²⁴_D - 97° (C = 1 in chloroform).

3. It has uvmax (methanol): 228, 302 nm (log ε 4.79, 4.48).

4. Solubility Profile: It is moderately soluble in methanol, benzene, chloroform and other organic solvents; and practically insoluble in water.

Uses It is mostly used as an antihypertensive.
Source:Pharmacognosy And Pharmacobiotechnology By Ashutosh Kar