Oripavine-Synonym O3-Demethylthebaine-Papaver bracteatum

E. Oripavine

Synonym O³-Demethylthebaine.

Biological Sources It is obtained from the plant Papaver bracteatum Lindl. (Papaveraceae) (Great Scarlet Poppy, Thebaine Poppy); and Papaver orientale Linn. (Papaveraceae).

Chemical Structure

(5α)-6, 7, 8, 14-Tetrahydro-4, 5-epoxy-6-methoxy-17-methyl-morphinan-3-ol; (C₁₈H₁₉NO₃).

Isolation It has been isolated from plant source by Kiselev and Konovalova.*

Characteristic Features The crystals have mp 200-201°C; and [α]_D²⁰  -211.8⁰.

Identification Tests

1. Oripavine Hydrochloride (C₁₈H₁₉NO₃.HCl): It is obtained as crystals which decompose at 244-245°C.

2. Oripavine Methiodide (C₁₈H₁₉NO₃.CH₃I): The crystals decompose at 207-208°C.
Source:Pharmacognosy And Pharmacobiotechnology By Ashutosh Kar