Mei Hu, Kazunori Ogawa, Yutaka Sashida Xiao Pei-Gen (1995), Triterpenoid glucuronide saponins from root bark of aralia armata, Phytochemistry, Volume 39, Issue 1, P.179-184
Abstract
Seventeen
oleanane-type saponins were isolated from the root bark of Aralia armata. Their
structures were elucidated by chemical and spectral evidence. Except for
oleanolic acid 28-O-β-D-glucopyranoside all the saponins have a
glucuronopyranosyl residue at the C-3 position of the aglycones and other sugar
substitutes bind to glucuronic acid at positions C-3 and/or C-4. A comparison
of saponin constituents of this plant with other araliaceous plants is
provided.
Keywords
Aralia
armata; Araliaceae; root bark; triterpenoid saponin; oleanolic acid glucuronide
INTRODUCTION
It is
known that the
roots of several members of Aralia species have been used as folk
medicines for rheumatism, tonic and diabetes in
China, Japan and
Russia. In the early
part of the
sixties, Kochetkov et al.
[1] isolated physiologically active
saponins, aralosides A, B and C,
first from this
genus. Many triterpenoid
saponins
have recently
been isolated from
several Aralia species [2-9]. A.
armata (Wall.) Seem. is one of common herbal medicines of the genus
Aralia in China.
No chemical work, however, has
been done on this plant. The present paper deals
with the isolation
and structure determination of16 oleanolic acid-based
saponins along with a minor saponin of hederagenin from
the root bark
of this plant.
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